CDKN2C/p18-INK4C Rabbit Monoclonal Antibody [KO Validated]

Name: CDKN2C/p18-INK4C Rabbit Monoclonal Antibody [KO Validated]
SKU: KDXB200254
Availability: InStock

$110.00 – $430.00

SKU:KDXB200254 Categories:Monoclonal Antibodies

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	[KO Validated] CDKN2C/p18-INK4C
Observed Mol Wt	18kDa
Alternative Names	4C, INK4C, p18, p18-INK4C
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	1031
Gene ID	P42773
Potency (Clone Number)	ARC1289
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.