KRAS+HRAS+NRAS Rabbit Monoclonal Antibody

Name: KRAS+HRAS+NRAS Rabbit Monoclonal Antibody
SKU: KDXB207344
Availability: InStock

$110.00 – $430.00

SKU:KDXB207344 Categories:Monoclonal Antibodies

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	KRAS+HRAS+NRAS
Observed Mol Wt	18kDa
Alternative Names	NS6; CMNS; KRAS; NCMS; ALPS4; N-ras; NRAS1; KRAS+HRAS+NRAS
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	4893/3265/3845
Gene ID	P01111/P01112/P01116_
Potency (Clone Number)	ARC1112
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer; Cell Biology; Immunology; Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.