NLRP2 Rabbit Polyclonal Antibody

Name: NLRP2 Rabbit Polyclonal Antibody - KinesisDx
SKU: KDXB208907
Availability: InStock

Price range: $80.00 through $350.00

SKU:KDXB208907 Categories:Cell Biology, Developmental Biology, Immunology, Polyclonal Antibodies

This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	NLRP2
Observed Mol Wt	121kDa
Alternative Names	NBS1; PAN1; NALP2; PYPAF2; CLR19.9; NLRP2
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.09% Sodium azide, pH7.3
Reactivity	Human, Mouse
Uniprot ID	55655
Gene ID	Q9NX02
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology; Developmental Biology; Immunology
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.