Phospho-NF2-S518 Rabbit Polyclonal Antibody

Name: Phospho-NF2-S518 Rabbit Polyclonal Antibody
SKU: KDXB210353
Availability: InStock

$100.00 – $430.00

SKU:KDXB210353 Categories:Phosphorylated Antibodies

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of this protein’s function has been implicated in tumorigenesis and metastasis. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities.

Pack Size	100ul, 1ml, 20ul
Applications	WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Phosphorylated Antibody
Organism Species	Human
Product Synonyms	Phospho-NF2-S518
Observed Mol Wt	70kDa
Alternative Names	ACN; SCH; BANF; merlin-1; Phospho-NF2-S518
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	4771
Gene ID	P35240
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Adhesion, Cell Biology, Immunology, Neuroscience
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.