This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, IF/ICC, IHC-P, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Polyclonal Antibody  | 
		
| Organism Species | Human  | 
		
| Product Synonyms | BSCL2  | 
		
| Observed Mol Wt | 44kDa  | 
		
| Alternative Names | HMN5; PELD; HMN5C; SPG17; GNG3LG; BSCL2  | 
		
| Immunogen (Antigen) | Recombinant protein  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 50% glycerol, PBS with 0.01% thimerosal, pH7.3  | 
		
| Reactivity | Human, Mouse, Rat  | 
		
| Uniprot ID | 26580  | 
		
| Gene ID | Q96G97  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Neuroscience; Diabetes;  | 
		
| KD/KO Validated | KD Validated  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
				    
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