This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.
| Pack Size | 100ul, 1ml, 20ul | 
|---|---|
| Applications | ELISA, IHC-P, WB | 
| Host Species | Rabbit | 
| Ig Isotype | IgG | 
| Antibody Type | Polyclonal Antibody | 
| Organism Species | Human | 
| Product Synonyms | BTNL2 | 
| Observed Mol Wt | 50kDa | 
| Alternative Names | SS2; BTN7; BTL-II; HSBLMHC1; BTNL2 | 
| Immunogen (Antigen) | Recombinant protein | 
| Format | Liquid | 
| Buffer Formulation | 50% glycerol, PBS with 0.05% proclin300, pH7.3 | 
| Reactivity | Human, Mouse, Rat | 
| Uniprot ID | 56244 | 
| Gene ID | Q9UIR0 | 
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography | 
| Usage | For Research Use Only. Not for diagnostics or human use. | 
| Shelf Life | 12 months at time of shipping | 
| Shipping | Shipped in Dry Ice at -20 Degree Celsius | 
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. | 
| Research Areas | Immunology, Inflammation | 
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. | 
 
				    
![CTCF Rabbit Polyclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A18627_N6060-4_KO-WB_01-370x444.jpg)

![ABCA6 Rabbit Polyclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A21243_Q12592_WB_01-370x444.jpg)

![Bcl-2 Rabbit Polyclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A21592_N1199-4C_WB_01-370x444.jpg)
![EGFR Rabbit Polyclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A11082_N11999-5_WB_01-370x444.jpg)
Reviews
There are no reviews yet.