The protein encoded by this gene is a member of the G protein-coupled receptor family.This receptor was identified as a gene induced by the Epstein-Barr virus (EBV),and is thought to be a mediator of EBV effects on B lymphocytes.This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.It has been shown to control the migration of memory T cells to inflamed tissues,as well as stimulate dendritic cell maturation.The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.Signals mediated by this receptor regulate T cell homeostasis in lymph nodes,and may also function in the activation and polarization of T cells,and in chronic inflammation pathogenesis.Alternative splicing of this gene results in multiple transcript variants.
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, IF/ICC, IHC-P, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Monoclonal Antibody  | 
		
| Organism Species | Human  | 
		
| Product Synonyms | CCR7  | 
		
| Observed Mol Wt | 43kDa  | 
		
| Alternative Names | BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7; CCR7  | 
		
| Immunogen (Antigen) | synthetic peptide  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 0.05% BSA, 50% glycerol, Buffer:PBS with 0.02% sodium azide, pH7.3  | 
		
| Reactivity | Human, Mouse, Rat  | 
		
| Uniprot ID | 1236  | 
		
| Gene ID | P32248  | 
		
| Potency (Clone Number) | ARC0231  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Cancer, Cell Biology, Immunology, Inflammation  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
				    
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