CDC42 Rabbit Polyclonal Antibody

Name: CDC42 Rabbit Polyclonal Antibody
SKU: KDXB202913
Availability: InStock

$80.00 – $350.00

SKU:KDXB202913 Categories:Polyclonal Antibodies

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Product Synonyms	CDC42
Observed Mol Wt	21kDa
Alternative Names	TKS; G25K; CDC42Hs; CDC42
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human
Uniprot ID	998
Gene ID	P60953
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Adhesion, Cell Biology, Immunology, Inflammation
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.