The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, IF/ICC, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Monoclonal Antibody |
| Organism Species | Human |
| Concentration | – |
| Product Synonyms | IL1RA |
| Observed Mol Wt | 20kDa |
| Alternative Names | DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA |
| Immunogen (Antigen) | Recombinant protein |
| Format | Liquid |
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3 |
| Reactivity | Human, Mouse, Rat |
| Uniprot ID | 3557 |
| Gene ID | P18510 |
| Potency (Clone Number) | ARC0524 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Growth factors, Immunology, Inflammation |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |

![ISG15 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A2416_ARC53794-01_KO-WB_01-370x444.jpg)
![GPX4 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A11243_ARC0558-03_WB_01-370x444.jpg)
![Heme Oxygenase 1 (HO-1/HMOX1) Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19062_ARC53508-01_WB_01-370x444.jpg)
![glucose-6-phosphate isomerase Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A4401_ARC0997_WB_01-370x444.jpg)
![Integrin alpha 5 (ITGA5/CD49e) Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A22706_ARC58291-01_WB_01-370x444.jpg)
![LC3B Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19665_ARC0144_WB_01-370x444.jpg)
Reviews
There are no reviews yet.