Ku80 Rabbit Monoclonal Antibody

Name: Ku80 Rabbit Monoclonal Antibody
SKU: KDXB207361
Availability: InStock

$110.00 – $430.00

SKU:KDXB207361 Categories:Monoclonal Antibodies

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, IHC-P, IP, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	Ku80
Observed Mol Wt	83kDa
Alternative Names	KU80; KUB2; Ku86; NFIV; KARP1; KARP-1; Ku80
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse
Uniprot ID	7520
Gene ID	P13010
Potency (Clone Number)	ARC0706
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology; Developmental Biology; Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.