Serine-threonine kinase that acts as a negative regulator of brassinosteroid (BR) signaling. Phosphorylates DLT and BZR1, two positive regulators that mediates several BR responses. Phosphorylation of DLT and BZR1 inhibits their activities in BR signaling. Phosphorylates OFP8, a positive regulator of BR responses. Phosphorylated OFP8 shuttles from the nucleus to the cytoplasm where it is degraded by the proteasome. Phosphorylates the E3 ubiquitin-protein ligase PUB24, a negative regulator of BR signaling, which targets BZR1 and promotes its degradation via the 26S proteasome. Phosphorylation of PUB24 increases its stability. Phosphorylates the AP2-ERF transcription factor SMOS1, a positive regulator of BR signaling, which cooperatively functions in a transactivating complex with BZR1 to enhance the transcription of BR biosynthetic genes. Phosphorylation of SMOS1 leads to its degradation by an unknown mechanism.
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Polyclonal Antibody |
| Organism Species | Oryza sativa |
| Concentration | – |
| Product Synonyms | OsGSK2 |
| Observed Mol Wt | 46kDa |
| Alternative Names | GSK2; SK22; OsGSK2; OsSK22; OJ1430_B02.4 |
| Immunogen (Antigen) | synthetic peptide |
| Format | Liquid |
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3 |
| Reactivity | Oryza sativa |
| Uniprot ID | 4338079 |
| Gene ID | Q60EZ2 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cell Biology, Developmental Biology, Immunology |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |

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