Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

![ISG15 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A2416_ARC53794-01_KO-WB_01-370x444.jpg)
![KMT5A/SETD8 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A4136_ARC0916_WB_01-370x444.jpg)
![CDX2 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19030_ARC0450_WB_01-370x444.jpg)
![BUB1 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A23198_ARC59688-01_KO-WB_01-370x444.jpg)
![MRP4/ABCC4 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A22601_ARC52223-01_WB_01-370x444.jpg)
![IRAK4 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A20839_ARC51289-01_KO-WB_01-370x444.jpg)
Reviews
There are no reviews yet.