Phospho-MRE11 (Ser676) Rabbit Polyclonal Antibody

Name: Phospho-MRE11 (Ser676) Rabbit Polyclonal Antibody
SKU: KDXB210335
Availability: InStock

$100.00 – $430.00

SKU:KDXB210335 Categories:Phosphorylated Antibodies

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3′ to 5′ exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3′ to 5′ exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Pack Size	100ul, 1ml, 20ul
Applications	WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Phosphorylated Antibody
Organism Species	Human
Product Synonyms	Phospho-MRE11 (Ser676)
Observed Mol Wt	81kDa
Alternative Names	ATLD; HNGS1; MRE11A; MRE11B; Phospho-MRE11 (Ser676)
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.05% proclin300, pH7.3
Reactivity	Human
Uniprot ID	4361
Gene ID	P49959
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.