This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
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| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Phosphorylated Antibody |
| Organism Species | Human |
| Product Synonyms | Phospho-MYL12A-S18 |
| Observed Mol Wt | 20kDa |
| Alternative Names | MLCB; MRCL3; MRLC3; MYL2B; MLC-2B; HEL-S-24; Phospho-MYL12A-S18 |
| Immunogen (Antigen) | synthetic peptide |
| Format | Liquid |
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3 |
| Reactivity | Human, Rat |
| Uniprot ID | 10627 |
| Gene ID | P19105 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cancer, Cell Biology, Immunology |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
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