Phospho-PKR/EIF2AK2-T446 Rabbit Monoclonal Antibody

Name: Phospho-PKR/EIF2AK2-T446 Rabbit Monoclonal Antibody
SKU: KDXB210462
Availability: InStock

$110.00 – $430.00

SKU:KDXB210462 Categories:Monoclonal Antibodies

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Phosphorylated Antibody
Organism Species	Human
Product Synonyms	Phospho-PKR/EIF2AK2-T446
Observed Mol Wt	62kDa
Alternative Names	PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83; Phospho-PKR/EIF2AK2-T446
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human
Uniprot ID	5610
Gene ID	P19525
Potency (Clone Number)	ARC0293
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.