SERCA2/ATP2A2 Rabbit Polyclonal Antibody

Name: SERCA2/ATP2A2 Rabbit Polyclonal Antibody
SKU: KDXB212383
Availability: InStock

$80.00 – $350.00

SKU:KDXB212383 Categories:Polyclonal Antibodies

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IHC-P, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Product Synonyms	SERCA2/ATP2A2
Observed Mol Wt	115kDa
Alternative Names	DD; DAR; ATP2B; SERCA2; SERCA2/ATP2A2
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.01% thimerosal, pH7.3
Reactivity	Mouse, Rat
Uniprot ID	488
Gene ID	P16615
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Neuroscience
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.