RNA methylation plays a significant regulatory role in various of physiological activities. 2′-O-methylcytidine (Cm) is one of the representative 2′-O-methylation and base-methylation modified epigenetic marks of RNA. 2′-O-Methylcytidine is derivative of the nucleoside residue cytidine with a methyl group attached to the 2′-oxygen position. 2?-O-methylcytidine was found to be related to various diseases including cancer, and it might have great potential to be novel biomarkers for detection of breast cancer in the early stage. In addition, 2′-O-methylcytidine showed as an inhibitor of RNA polymerase from the hepatitis C virus (HCV). And 2?-O-methylcytidine was involved in plant stress responses.

Pack Size

100ul, 1ml, 20ul

Applications

DB, ELISA

Host Species

Rabbit

Ig Isotype

IgG

Antibody Type

Other Modified Antibody

Organism Species

Human

Concentration

Product Synonyms

2'-O-methylcytidine/ Cm

Alternative Names

2'-O-methylcytidine, 2'-O-methylcytidine/ Cm, Cm

Immunogen (Antigen)

Chemical compounds

Format

Liquid

Buffer Formulation

0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3

Reactivity

Species independent

Potency (Clone Number)

ARC50639

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Usage

For Research Use Only. Not for diagnostics or human use.

Shelf Life

12 months at time of shipping

Shipping

Shipped in Dry Ice at -20 Degree Celsius

Storage

Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.

Research Areas

Cell Biology, Developmental Biology, Immunology

KD/KO Validated

KD Validated

Disclaimer

The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.

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