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Cell Biology

2′-O-methyluridine(Um) Rabbit Polyclonal Antibody

Name: 2'-O-methyluridine(Um) Rabbit Polyclonal Antibody
SKU: KDXB200733
Availability: InStock

$80.00 – $350.00

SKU:KDXB200733 Categories:Polyclonal Antibodies

RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2′-O-methyladenosine (Am), 2′-O-methylguanosine (Gm),2′-O-methylcytidine (Cm),2′-O-methyluridine (Um),N 6-methyladenosine (m6A), N 1-methylguanosine (m1G),5-methylcytidine (m5C),and 5-methyluridine (m5U) are representative 2′-O-methylation and base-methylation modified epigenetic marks of RNA. 2′-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2′-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2′-O-methylguanosine is thought to stabilize the structure of the tRNA.

Pack Size	100ul, 1ml, 20ul
Applications	DB, ELISA
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	2'-O-methyluridine(Um)
Alternative Names	2'-O-methyluridine, 2'-O-methyluridine(Um), Um
Immunogen (Antigen)	Chemical compounds
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.01% thimerosal, pH7.3
Reactivity	Species independent
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology, Developmental Biology, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.