In mammalian genomes, 5-mC can be enzymatically oxidized to 5-hmC (5-hydroxymethylcytosine). This modification is suggested to be an intermediate between methylation and demethylation of the genome. Occupancy of 5-hmC correlates with inactive or non-productive promoters (PMID: 21925312). 5-hmC pattern is different from 5-methylcytosine (5-mC) in many instances(PMID: 21610077).

Pack Size

100ul, 1ml, 20ul

Applications

DB, ELISA

Host Species

Rabbit

Ig Isotype

IgG

Antibody Type

Polyclonal Antibody

Concentration

Product Synonyms

5-Hydroxymethylcytosine/ 5-hmC

Alternative Names

5-hmC, 5-HydroxyMethyl cytidine, 5-Hydroxymethylcytosine/ 5-hmC, 5hmc, hm5c

Format

Liquid

Buffer Formulation

50% glycerol, PBS with 0.01% thimerosal, pH7.3

Reactivity

Human, Mouse, Other (Wide Range Predicted), Rat

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Usage

For Research Use Only. Not for diagnostics or human use.

Shelf Life

12 months at time of shipping

Shipping

Shipped in Dry Ice at -20 Degree Celsius

Storage

Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.

Research Areas

Cell Biology, Developmental Biology, Immunology

KD/KO Validated

KD Validated

Disclaimer

The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.

Reviews

There are no reviews yet.

Be the first to review “5-Hydroxymethylcytosine/ 5-hmC Rabbit Polyclonal Antibody”

Your email address will not be published. Required fields are marked *