5-Hydroxymethylcytosine/ 5-hmC Rabbit Polyclonal Antibody

Name: 5-Hydroxymethylcytosine/ 5-hmC Rabbit Polyclonal Antibody
SKU: KDXB200740
Availability: InStock

$80.00 – $350.00

SKU:KDXB200740 Categories:Polyclonal Antibodies

In mammalian genomes, 5-mC can be enzymatically oxidized to 5-hmC (5-hydroxymethylcytosine). This modification is suggested to be an intermediate between methylation and demethylation of the genome. Occupancy of 5-hmC correlates with inactive or non-productive promoters (PMID: 21925312). 5-hmC pattern is different from 5-methylcytosine (5-mC) in many instances(PMID: 21610077).

Pack Size	100ul, 1ml, 20ul
Applications	DB, ELISA
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Concentration	–
Product Synonyms	5-Hydroxymethylcytosine/ 5-hmC
Alternative Names	5-hmC, 5-HydroxyMethyl cytidine, 5-Hydroxymethylcytosine/ 5-hmC, 5hmc, hm5c
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.01% thimerosal, pH7.3
Reactivity	Human, Mouse, Other (Wide Range Predicted), Rat
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology, Developmental Biology, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.