Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been found for this gene.
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, IHC-P, IP, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Monoclonal Antibody  | 
		
| Organism Species | Human  | 
		
| Concentration | –  | 
		
| Product Synonyms | ACC1  | 
		
| Observed Mol Wt | 266kDa  | 
		
| Alternative Names | ACAC, Acac1, ACACAD, ACACalpha, ACC, ACC1, ACCA, ACCalpha, hACC1  | 
		
| Immunogen (Antigen) | synthetic peptide  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3  | 
		
| Reactivity | Human, Mouse, Rat  | 
		
| Uniprot ID | 31  | 
		
| Gene ID | Q13085  | 
		
| Potency (Clone Number) | ARC2201  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Cancer, Cell Biology, Immunology  | 
		
| KD/KO Validated | KD Validated  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
				    
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