ALPK1 Rabbit Polyclonal Antibody

Name: ALPK1 Rabbit Polyclonal Antibody
SKU: KDXB201272
Availability: InStock

$80.00 – $350.00

SKU:KDXB201272 Categories:Polyclonal Antibodies

Alpha-protein kinase 1, also known as alpha-kinase 1 (ALPK1), is associated with chronic kidney disease (CKD), myocardial infarction, gout and type 2 diabetes mellitus (DM). ALPK1 mutant has been reported to cause severe defects in motor co?ordination in mice. ALPK1 enhances the expression of proinflammatory cytokines including IL-1Beta, IL-8 and TGF-Beta1 in cultured human THP1 and human embryonic kidney 293 (HEK293) cells . ALPK1 short isoform (108 kDa) was highly expressed in brain, spinal cord, heart, lung, spleen, thymus, small intestine, skin and testis, while detectable inskeletal muscle and kidney. ALPK1 large isoform (130 kDa) appeared in heart, lung, thymus and skin.

Pack Size	100ul, 1ml, 20ul
Applications	WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Product Synonyms	ALPK1
Observed Mol Wt	139kDa
Alternative Names	LAK; ROSAH; 8430410J10Rik; ALPK1
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.05% proclin300, pH7.3
Reactivity	Human
Uniprot ID	80216
Gene ID	Q96QP1
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer; Cell Biology; Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.