The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.
| Pack Size | 100ul, 1ml, 20ul | 
|---|---|
| Applications | ELISA, WB | 
| Host Species | Rabbit | 
| Ig Isotype | IgG | 
| Antibody Type | Monoclonal Antibody | 
| Organism Species | Human | 
| Product Synonyms | Axl | 
| Observed Mol Wt | 98kDa | 
| Alternative Names | ARK; UFO; JTK11; Tyro7; Axl | 
| Immunogen (Antigen) | Recombinant protein | 
| Format | Liquid | 
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3 | 
| Reactivity | Human, Mouse | 
| Uniprot ID | 558 | 
| Gene ID | P30530 | 
| Potency (Clone Number) | ARC53006 | 
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography | 
| Usage | For Research Use Only. Not for diagnostics or human use. | 
| Shelf Life | 12 months at time of shipping | 
| Shipping | Shipped in Dry Ice at -20 Degree Celsius | 
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. | 
| Research Areas | Cancer; Cell Biology; Immunology; Inflammation | 
| KD/KO Validated | KD Validated | 
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. | 
 
				    
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