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Cancer

c-Myc Mouse Monoclonal Antibody

Name: c-Myc Mouse Monoclonal Antibody
SKU: KDXB203356
Availability: InStock

$110.00 – $430.00

SKU:KDXB203356 Categories:Monoclonal Antibodies

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, IP, WB
Host Species	Rabbit
Ig Isotype	IgG1, kappa
Antibody Type	Monoclonal Antibody
Organism Species	Human
Product Synonyms	c-Myc
Observed Mol Wt	51kDa
Alternative Names	MRTL; MYCC; c-Myc; bHLHe39
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	4609
Gene ID	P01106
Potency (Clone Number)	AMC0489
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.