This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Polyclonal Antibody  | 
		
| Organism Species | Human  | 
		
| Product Synonyms | Caspase-2  | 
		
| Observed Mol Wt | 51kDa  | 
		
| Alternative Names | ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; Caspase-2  | 
		
| Immunogen (Antigen) | Recombinant protein  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3  | 
		
| Reactivity | Human, Mouse, Rat  | 
		
| Uniprot ID | 835  | 
		
| Gene ID | P42575  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Cancer, Cell Biology, Immunology, Inflammation  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
				    
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