The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Monoclonal Antibody  | 
		
| Organism Species | Human  | 
		
| Product Synonyms | CCR2/CKR2  | 
		
| Observed Mol Wt | 42kDa  | 
		
| Alternative Names | CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; CCR2/CKR2  | 
		
| Immunogen (Antigen) | synthetic peptide  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3  | 
		
| Reactivity | Human, Mouse, Rat  | 
		
| Uniprot ID | 729230  | 
		
| Gene ID | P41597  | 
		
| Potency (Clone Number) | ARC2585  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Cancer, Cell Biology, Immunology, Inflammation  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
				    
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