ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | FC, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG1 |
| Antibody Type | Monoclonal Antibody |
| Organism Species | Human |
| Product Synonyms | CD11a |
| Observed Mol Wt | 118kDa/129kDa/134kDa |
| Alternative Names | CD11A; LFA-1; LFA1A; CD11a |
| Immunogen (Antigen) | Recombinant protein |
| Format | Liquid |
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
| Reactivity | Human |
| Uniprot ID | 3683 |
| Gene ID | P20701 |
| Potency (Clone Number) | ARC62732 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cancer, Cell Adhesion, Cell Biology, Immunology, Inflammation |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |


![Casein Kinase 2 alpha (CSNK2A1) Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19683_ARC0163_WB_01-370x444.jpg)
![IL13 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A23415_ARC61007-01_KO-WB_01-370x444.jpg)
![CDX2 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A20222_ARC3070_KO-WB_01-370x444.jpg)
![EGFR Rabbit PolyMonoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A24388_ARC61438-01_ARC60682-01_KO-WB_01-370x444.jpg)
![ATG7 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19604_ARC0083_WB_01-370x444.jpg)
Reviews
There are no reviews yet.