Enables death receptor activity; nerve growth factor binding activity; and small GTPase binding activity. Involved in several processes, including cellular glucose homeostasis; circadian regulation of gene expression; and dorsal aorta development. Acts upstream of or within several processes, including hair follicle morphogenesis; nervous system development; and regulation of signal transduction. Located in several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer’s disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor).
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, FC, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Monoclonal Antibody |
| Organism Species | Mouse |
| Product Synonyms | CD271 |
| Observed Mol Wt | 45kDa |
| Alternative Names | p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16; CD271 |
| Immunogen (Antigen) | Recombinant protein |
| Format | Liquid |
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
| Reactivity | Mouse, Rat |
| Uniprot ID | 18053 |
| Gene ID | Q9Z0W1 |
| Potency (Clone Number) | ARC62149 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Growth factors, Neuroscience |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |

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