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Cancer

Claudin18.2 Rabbit Monoclonal Antibody

Name: Claudin18.2 Rabbit Monoclonal Antibody
SKU: KDXB203265
Availability: InStock

$110.00 – $430.00

SKU:KDXB203265 Categories:Monoclonal Antibodies

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IHC-P
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Product Synonyms	Claudin18.2
Observed Mol Wt	28kDa
Alternative Names	SFTA5; SFTPJ; Claudin18.2
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3
Reactivity	Human
Uniprot ID	51208
Gene ID	P56856
Potency (Clone Number)	ARC5062-02
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Adhesion, Cell Biology, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.