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Cancer

Cleaved IL-18 (Tyr37) Rabbit Monoclonal Antibody

Name: Cleaved IL-18 (Tyr37) Rabbit Monoclonal Antibody
SKU: KDXB203295
Availability: InStock

$110.00 – $430.00

SKU:KDXB203295 Categories:Monoclonal Antibodies

The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Pack Size	100ul, 1ml, 20ul
Applications	WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Product Synonyms	Cleaved IL-18 (Tyr37)
Observed Mol Wt	22kDa
Alternative Names	mature IL-18; Cleaved IL-18 (Tyr37)
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3
Reactivity	Human
Uniprot ID	3606
Gene ID	Q14116
Potency (Clone Number)	ARC64645
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Growth factors, Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.