NAD+, as a key coenzyme in eukaryotic organisms, determines hundreds of enzymatic reactions. The coenzyme NAD is involved in oxidation?reduction reactions critical for glycolysis, fatty acid oxidation, the TCA cycle, and complex I of the mitochondrial respiratory chain and also is a key regulator of autophagy. In addition, NAD+ can also indirectly regulate the process of anti-stress, cell growth, anti-inflammatory and anti-aging processes by regulating the function of Sirtuins factor which has NAD+ dependent protein deacetylation activity. The decline of NAD+ level will also lead to heart failure and Alzheimer’s disease.

Pack Size

100ul, 1ml, 20ul

Applications

DB, ELISA

Host Species

Rabbit

Ig Isotype

IgG

Antibody Type

Polyclonal Antibody

Product Synonyms

Coenzyme NAD

Immunogen (Antigen)

Chemical compounds

Format

Liquid

Buffer Formulation

50% glycerol, PBS with 0.05% proclin300, pH7.3

Reactivity

Species independent

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Usage

For Research Use Only. Not for diagnostics or human use.

Shelf Life

12 months at time of shipping

Shipping

Shipped in Dry Ice at -20 Degree Celsius

Storage

Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.

Research Areas

Cell Biology, Developmental Biology, Immunology

KD/KO Validated

KD Validated

Disclaimer

The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.

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