This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.
Pack Size | 100ul, 1ml, 20ul |
---|---|
Applications | ELISA, WB |
Host Species | Rabbit |
Ig Isotype | IgG |
Antibody Type | Polyclonal Antibody |
Organism Species | Human |
Product Synonyms | CRTC2 |
Observed Mol Wt | 73kDa |
Alternative Names | TORC2; TORC-2; CRTC2 |
Immunogen (Antigen) | Recombinant protein |
Format | Liquid |
Buffer Formulation | 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
Reactivity | Human |
Uniprot ID | 200186 |
Gene ID | Q53ET0 |
Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
Usage | For Research Use Only. Not for diagnostics or human use. |
Shelf Life | 12 months at time of shipping |
Shipping | Shipped in Dry Ice at -20 Degree Celsius |
Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
Research Areas | Cancer, Cell Biology, Hormone Metabolism, Immunology, Neuroscience |
KD/KO Validated | KD Validated |
Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
Related Products
-
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist
Reviews
There are no reviews yet.