This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, IF/ICC, IHC-P, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Polyclonal Antibody |
| Organism Species | Human |
| Product Synonyms | DCN |
| Observed Mol Wt | 40kDa |
| Alternative Names | CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B; DCN |
| Immunogen (Antigen) | synthetic peptide |
| Format | Liquid |
| Buffer Formulation | 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
| Reactivity | Human, Mouse, Rat |
| Uniprot ID | 1634 |
| Gene ID | P07585 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Bone Metabolism, Cancer, Cell Biology, Immunology, Mesenchymal Stem Cells |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
Related Products
-
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist

Reviews
There are no reviews yet.