This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8.

Pack Size

100ul, 1ml, 20ul

Applications

ELISA, IHC-P

Host Species

Rabbit

Ig Isotype

IgG1, kappa

Antibody Type

Monoclonal Antibody

Organism Species

Mouse

Product Synonyms

E-Cadherin

Observed Mol Wt

98kDa

Alternative Names

Um; UVO; Ecad; ARC-1; E-cad; L-CAM; E-Cadherin

Immunogen (Antigen)

Recombinant protein

Format

Liquid

Buffer Formulation

0.2% BSA, 40% glycerol, PBS with 0.05% sodium azide, pH7.4.

Reactivity

Human, Mouse, Rat

Uniprot ID

12550

Gene ID

P09803

Potency (Clone Number)

AMC0478

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Usage

For Research Use Only. Not for diagnostics or human use.

Shelf Life

12 months at time of shipping

Shipping

Shipped in Dry Ice at -20 Degree Celsius

Storage

Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.

Research Areas

Cancer, Cell Biology, Immunology, Inflammation, NeuroscienceCD MarkersCell Adhesion

KD/KO Validated

KD Validated

Disclaimer

The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.

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