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Histone H2A.Z Rabbit Monoclonal Antibody [KO Validated]

Name: Histone H2A.Z Rabbit Monoclonal Antibody [KO Validated] - KinesisDx
SKU: KDXB200371
Availability: InStock

Price range: $110.00 through $430.00

SKU:KDXB200371 Categories:Monoclonal Antibodies

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Pack Size	100ul, 1ml, 20ul
Applications	ChIP, ELISA, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	[KO Validated] Histone H2A.Z
Observed Mol Wt	13kDa
Alternative Names	.Z, H2A.z, H2A.Z-1, H2A/z, H2AFZ, H2AZ
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Other (Wide Range Predicted), Rat
Uniprot ID	3015
Gene ID	P0C0S5
Potency (Clone Number)	ARC1048
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology, Developmental Biology, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.