Enables NF-kappaB binding activity and heat shock protein binding activity. Involved in several processes, including cytoplasmic sequestering of NF-kappaB, leukocyte migration involved in inflammatory response, and liver regeneration. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Located in cytosol and nucleus. Part of protein-containing complex. Used to study gastritis, pulmonary emphysema, and sciatic neuropathy. Biomarker of several diseases, including acute necrotizing pancreatitis, alcoholic hepatitis, artery disease (multiple), middle cerebral artery infarction, and toxic shock syndrome. Human ortholog(s) of this gene implicated in several diseases, including childhood-onset asthma, hematologic cancer (multiple), hepatitis B, hepatitis C, and lung disease (multiple). Orthologous to human NFKBIA (NFKB inhibitor alpha).

Pack Size

100ul, 1ml, 20ul

Applications

ELISA, WB

Host Species

Rabbit

Ig Isotype

IgG

Antibody Type

Polyclonal Antibody

Organism Species

Rat

Concentration

Product Synonyms

[KO Validated] I?BAlpha

Observed Mol Wt

35kDa

Alternative Names

BAlpha, RL/IF-1

Immunogen (Antigen)

Recombinant protein

Format

Liquid

Buffer Formulation

50% glycerol, PBS with 0.02% sodium azide, pH7.3

Reactivity

Human, Mouse, Rat

Uniprot ID

25493

Gene ID

Q63746

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Usage

For Research Use Only. Not for diagnostics or human use.

Shelf Life

12 months at time of shipping

Shipping

Shipped in Dry Ice at -20 Degree Celsius

Storage

Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.

Research Areas

Cell Biology, Developmental Biology, Immunology

KD/KO Validated

KD Validated

Disclaimer

The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.

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