Enables NF-kappaB binding activity and heat shock protein binding activity. Involved in several processes, including cytoplasmic sequestering of NF-kappaB, leukocyte migration involved in inflammatory response, and liver regeneration. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Located in cytosol and nucleus. Part of protein-containing complex. Used to study gastritis, pulmonary emphysema, and sciatic neuropathy. Biomarker of several diseases, including acute necrotizing pancreatitis, alcoholic hepatitis, artery disease (multiple), middle cerebral artery infarction, and toxic shock syndrome. Human ortholog(s) of this gene implicated in several diseases, including childhood-onset asthma, hematologic cancer (multiple), hepatitis B, hepatitis C, and lung disease (multiple). Orthologous to human NFKBIA (NFKB inhibitor alpha).
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Polyclonal Antibody |
| Organism Species | Rat |
| Concentration | – |
| Product Synonyms | [KO Validated] I?BAlpha |
| Observed Mol Wt | 35kDa |
| Alternative Names | BAlpha, RL/IF-1 |
| Immunogen (Antigen) | Recombinant protein |
| Format | Liquid |
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3 |
| Reactivity | Human, Mouse, Rat |
| Uniprot ID | 25493 |
| Gene ID | Q63746 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cell Biology, Developmental Biology, Immunology |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
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