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Cancer

IDO1 Rabbit Monoclonal Antibody

Name: IDO1 Rabbit Monoclonal Antibody
SKU: KDXB206588
Availability: InStock

$110.00 – $430.00

SKU:KDXB206588 Categories:Monoclonal Antibodies

This gene encodes indoleamine 2,3-dioxygenase (IDO) – a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IHC-P
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	IDO1
Observed Mol Wt	45kDa
Alternative Names	IDO; INDO; IDO-1; IDO1
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse
Uniprot ID	3620
Gene ID	P14902
Potency (Clone Number)	ARC0560
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.