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Cancer

IMPDH2 Rabbit Monoclonal Antibody [KO Validated]

Name: IMPDH2 Rabbit Monoclonal Antibody [KO Validated]
SKU: KDXB200405
Availability: InStock

$110.00 – $430.00

SKU:KDXB200405 Categories:Monoclonal Antibodies

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5′-monophosphate into xanthine-5′-monophosphate, which is then converted into guanosine-5′-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Monoclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	[KO Validated] IMPDH2
Observed Mol Wt	56kDa
Alternative Names	H2, IMPD2, IMPDH-II
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	3615
Gene ID	P12268
Potency (Clone Number)	ARC1479
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Growth factors, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.