This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, IF/ICC, IHC-P, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Polyclonal Antibody  | 
		
| Organism Species | Human  | 
		
| Concentration | –  | 
		
| Product Synonyms | [KO Validated] Integrin alpha 2 (ITGA2/CD49b)  | 
		
| Observed Mol Wt | 129kDa  | 
		
| Alternative Names | b), BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2  | 
		
| Immunogen (Antigen) | synthetic peptide  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3  | 
		
| Reactivity | Human, Mouse, Rat  | 
		
| Uniprot ID | 3673  | 
		
| Gene ID | P17301  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Cancer, Cell Adhesion, Cell Biology, Immunology, Inflammation  | 
		
| KD/KO Validated | KD Validated  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
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