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Cell Biology

MCM7 Rabbit Polyclonal Antibody

Name: MCM7 Rabbit Polyclonal Antibody
SKU: KDXB207901
Availability: InStock

$80.00 – $350.00

SKU:KDXB207901 Categories:Polyclonal Antibodies

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, IP, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	MCM7
Observed Mol Wt	81kDa
Alternative Names	MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3; MCM7
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.05% proclin300, pH7.3
Reactivity	Human, Mouse
Uniprot ID	4176
Gene ID	P33993
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology; Developmental Biology; Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.