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Cell Biology

MonoMethyl-UHRF1-K385 Rabbit Polyclonal Antibody

Name: MonoMethyl-UHRF1-K385 Rabbit Polyclonal Antibody - KinesisDx
SKU: KDXB208209
Availability: InStock

Price range: $100.00 through $430.00

SKU:KDXB208209 Categories:Cell Biology, Developmental Biology, Immunology, Methylated Antibodies

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.

Pack Size	100ul, 1ml, 20ul
Applications	DB, ELISA, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Methylated Antibody
Organism Species	Human
Concentration	–
Product Synonyms	MonoMethyl-UHRF1-K385
Observed Mol Wt	90kDa
Alternative Names	Np95; hNP95; ICBP90; RNF106; TDRD22; hUHRF1; huNp95; MonoMethyl-UHRF1-K385
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	29128
Gene ID	Q96T88
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cell Biology; Developmental Biology; Immunology
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.