This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Osteocalcin (BGLAP) Rabbit Polyclonal Antibody
$80.00 – $350.00
| Pack Size | 100ul, 1ml, 20ul | 
|---|---|
| Applications | ELISA, IF/ICC, WB | 
| Host Species | Rabbit | 
| Ig Isotype | IgG | 
| Antibody Type | Polyclonal Antibody | 
| Organism Species | Human | 
| Concentration | – | 
| Product Synonyms | Osteocalcin (BGLAP) | 
| Observed Mol Wt | 11kDa | 
| Alternative Names | OC; BGP; OCN; Osteocalcin (BGLAP) | 
| Immunogen (Antigen) | synthetic peptide | 
| Format | Liquid | 
| Buffer Formulation | 50% glycerol, PBS with 0.05% proclin300, pH7.3 | 
| Reactivity | Human, Mouse, Rat | 
| Uniprot ID | 632 | 
| Gene ID | P02818 | 
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography | 
| Usage | For Research Use Only. Not for diagnostics or human use. | 
| Shelf Life | 12 months at time of shipping | 
| Shipping | Shipped in Dry Ice at -20 Degree Celsius | 
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. | 
| Research Areas | Bone Metabolism, Cancer, Cell Biology, Immunology, Mesenchymal Stem Cells | 
| KD/KO Validated | KD Validated | 
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. | 
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