This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Osteocalcin (BGLAP) Rabbit Polyclonal Antibody
$80.00 – $350.00
Pack Size | 100ul, 1ml, 20ul |
---|---|
Applications | ELISA, IF/ICC, WB |
Host Species | Rabbit |
Ig Isotype | IgG |
Antibody Type | Polyclonal Antibody |
Organism Species | Human |
Concentration | – |
Product Synonyms | Osteocalcin (BGLAP) |
Observed Mol Wt | 11kDa |
Alternative Names | OC; BGP; OCN; Osteocalcin (BGLAP) |
Immunogen (Antigen) | synthetic peptide |
Format | Liquid |
Buffer Formulation | 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
Reactivity | Human, Mouse, Rat |
Uniprot ID | 632 |
Gene ID | P02818 |
Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
Usage | For Research Use Only. Not for diagnostics or human use. |
Shelf Life | 12 months at time of shipping |
Shipping | Shipped in Dry Ice at -20 Degree Celsius |
Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
Research Areas | Bone Metabolism, Cancer, Cell Biology, Immunology, Mesenchymal Stem Cells |
KD/KO Validated | KD Validated |
Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
Related Products
-
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist
Reviews
There are no reviews yet.