This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
| Pack Size | 100ul, 1ml, 20ul | 
|---|---|
| Applications | ELISA, WB | 
| Host Species | Rabbit | 
| Ig Isotype | IgG | 
| Antibody Type | Polyclonal Antibody | 
| Organism Species | Human | 
| Concentration | – | 
| Product Synonyms | PAX3 | 
| Observed Mol Wt | 53kDa | 
| Alternative Names | WS1; WS3; CDHS; HUP2; PAX-3; PAX3 | 
| Immunogen (Antigen) | Recombinant protein | 
| Format | Liquid | 
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3 | 
| Reactivity | Human, Mouse, Rat | 
| Uniprot ID | 5077 | 
| Gene ID | P23760 | 
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography | 
| Usage | For Research Use Only. Not for diagnostics or human use. | 
| Shelf Life | 12 months at time of shipping | 
| Shipping | Shipped in Dry Ice at -20 Degree Celsius | 
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. | 
| Research Areas | Mesenchymal Stem Cells | 
| KD/KO Validated | KD Validated | 
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. | 
 
				    
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