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Cancer

Phospho-eIF2Alpha-S51 Rabbit Monoclonal Antibody

Name: Phospho-eIF2Alpha-S51 Rabbit Monoclonal Antibody
SKU: KDXB210116
Availability: InStock

$110.00 – $430.00

SKU:KDXB210116 Categories:Monoclonal Antibodies

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Phosphorylated Antibody
Organism Species	Human
Product Synonyms	Phospho-eIF2Alpha-S51
Observed Mol Wt	36kDa
Alternative Names	EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha; Phospho-eIF2Alpha-S51
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	1965
Gene ID	P05198
Potency (Clone Number)	ARC0130
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.