Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
- “Phospho-(Ser/Thr) ATM/ATR Substrate Rabbit Polyclonal Antibody” already exists in your wishlist
| Pack Size | 100ul, 1ml, 20ul | 
|---|---|
| Applications | WB | 
| Host Species | Rabbit | 
| Ig Isotype | IgG | 
| Antibody Type | Phosphorylated Antibody | 
| Organism Species | Human | 
| Product Synonyms | Phospho-HDAC4-S632 | 
| Observed Mol Wt | 119kDa | 
| Alternative Names | HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; NEDCHF; NEDCHID; Phospho-HDAC4-S632 | 
| Immunogen (Antigen) | synthetic peptide | 
| Format | Liquid | 
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3 | 
| Reactivity | Human, Mouse, Rat | 
| Uniprot ID | 9759 | 
| Gene ID | P56524 | 
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography | 
| Usage | For Research Use Only. Not for diagnostics or human use. | 
| Shelf Life | 12 months at time of shipping | 
| Shipping | Shipped in Dry Ice at -20 Degree Celsius | 
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. | 
| Research Areas | Cancer, Cell Biology, Immunology, Inflammation | 
| KD/KO Validated | KD Validated | 
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. | 
 
				    






Reviews
There are no reviews yet.