This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
| Pack Size | 100ul, 1ml, 20ul  | 
		
|---|---|
| Applications | ELISA, WB  | 
		
| Host Species | Rabbit  | 
		
| Ig Isotype | IgG  | 
		
| Antibody Type | Phosphorylated Antibody  | 
		
| Organism Species | Human  | 
		
| Product Synonyms | Phospho-PDGFR alpha-Y849  | 
		
| Observed Mol Wt | 123kDa  | 
		
| Alternative Names | CD140A; PDGFR2; PDGFR-2; Phospho-PDGFR alpha-Y849  | 
		
| Immunogen (Antigen) | synthetic peptide  | 
		
| Format | Liquid  | 
		
| Buffer Formulation | 50% glycerol, PBS with 0.02% sodium azide, pH7.3  | 
		
| Reactivity | Human  | 
		
| Uniprot ID | 5156  | 
		
| Gene ID | P16234  | 
		
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography  | 
		
| Usage | For Research Use Only. Not for diagnostics or human use.  | 
		
| Shelf Life | 12 months at time of shipping  | 
		
| Shipping | Shipped in Dry Ice at -20 Degree Celsius  | 
		
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.  | 
		
| Research Areas | Cancer, Cell Biology, Growth factors, Immunology, Inflammation  | 
		
| KD/KO Validated | KD Validated  | 
		
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.  | 
		
				    






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