Phospho-ZAP70-Y319 Rabbit Polyclonal Antibody

Name: Phospho-ZAP70-Y319 Rabbit Polyclonal Antibody
SKU: KDXB210665
Availability: InStock

$100.00 – $430.00

SKU:KDXB210665 Categories:Phosphorylated Antibodies

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IP, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Phosphorylated Antibody
Organism Species	Human
Product Synonyms	Phospho-ZAP70-Y319
Observed Mol Wt	70kDa
Alternative Names	SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70; Phospho-ZAP70-Y319
Immunogen (Antigen)	synthetic peptide
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.05% proclin300, pH7.3
Reactivity	Human
Uniprot ID	7535
Gene ID	P43403
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.