The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.

| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, IHC-P, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Monoclonal Antibody |
| Organism Species | Human |
| Product Synonyms | PSMB9/LMP2 |
| Observed Mol Wt | 23kDa |
| Alternative Names | LMP2; PRAAS3; PSMB6i; RING12; beta1i; PSMB9/LMP2 |
| Immunogen (Antigen) | Recombinant protein |
| Format | Liquid |
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.02% sodium azide, pH7.3 |
| Reactivity | Human, Mouse, Rat |
| Uniprot ID | 5698 |
| Gene ID | P28065 |
| Potency (Clone Number) | ARC1629 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cell Biology, Developmental Biology, Immunology |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
![ISG15 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A2416_ARC53794-01_KO-WB_01-370x444.jpg)
![BUB1 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A23198_ARC59688-01_KO-WB_01-370x444.jpg)
![DNMT1 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19679_ARC51348-01_WB_02-370x444.jpg)
![ATG7 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A19604_ARC0083_WB_01-370x444.jpg)
![EGFR Rabbit PolyMonoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A24388_ARC61438-01_ARC60682-01_KO-WB_01-370x444.jpg)
![IL13 Rabbit Monoclonal Antibody [KD Validated]](https://www.kinesisdx.com/wp-content/uploads/2025/05/A23415_ARC61007-01_KO-WB_01-370x444.jpg)
Reviews
There are no reviews yet.